Measure | Pre-term (N= 25) | Full-term (N= 3 9) | Probability values |
---|---|---|---|
Neonatal measures | |||
Gestational age/weeks | 28.7 (26–33) | 39.4 (37–42) | p< 0.001 |
Birth weight/g | 997.4 (700–1240) | 3394.8 (2212–4648) | p< 0.001 |
9th year measures | |||
Adjusted age*/yr | 8.6 | 8.7 | |
Height/cm | 127.8 | 132.1 | p<0.05 |
Full-scale IQ | 93.2 (49–126) | 116.7 (75–145) | p< 0.0001 |
KC (N = 66) | Control (N = 67) | Probability the difference between KC and the control mean arose by chance | |||
---|---|---|---|---|---|
mean | SD | mean | SD | ||
Birth weight/g | 1245 | 328 | 1289 | 358 | (no difference) |
Gestational age/weeks | 30.4 | 2.5 | 30.8 | 3.0 | (no difference) |
Mental development index (MDI) | 96.39 | 7.23 | 91.81 | 9.80 | p<0.01 |
Psychomotor index (PMI) | 85.47 | 18.42 | 80.53 | 13.33 | p<0.01 |
‘Looking back on their records of childhood abuse for the cohort, the researchers found an additional link between 5-HTT gene variants (s-allele and 1-allele ) and depression: Abuse as a child predicted depression after the age of 18 only in people carrying at least one s-allele. Among the 11% who had experienced severe maltreatment, the double s-allele subjects ran a 63% risk of a major depressive episode. The 1-allele participants averaged a 30% risk, regardless of whether they had been abused as children.’ (Holden, 2003)