from The Open University
Alternatively you can skip the navigation by pressing 'Enter'.
The Met: Policing London: Episode FourThursday, 2nd July 2015 00:10 - BBC OneThis episode of OU/BBC's The Met: Policing London looks at tackling the city's crime after dark - from... Read more: The Met: Policing London: Episode Four
The Met: Policing London: Episode FourThursday, 2nd July 2015 01:00 - BBC One
The Bottom Line: Summer 2015: The Bottom Line - Burger BattlesThursday, 2nd July 2015 20:30 - BBC Radio 4
The Bank: Love and MoneyThursday, 2nd July 2015 23:20 - BBC Two
The Bank: Love and MoneyAvailable until Sunday, 2nd August 2015 00:50The second episode of The Bank looks at love in relation to money - with everything from engagements, marriage,... Read more: The Bank: Love and Money
The Met: Policing London: Episode FourAvailable until Monday, 6th July 2015 22:00
Thinking Allowed: Factory music and volunteering post-recessionAvailable for over a year
Thinking Allowed: White working class boys and French thoughtAvailable for over a year
Video and Transcript - PolishAs part of an international project to get our International Year of Light animation... Read more: Video and Transcript - Polish
Take the photographic memory testCan you capture scenes just by looking at them? Find out with our photographic memory test. Launch now: Take the photographic memory test
Start writing fictionHave you always wanted to write, but never quite had the courage to start? This free course,... Try: Start writing fiction now
English: skills for learningThis course is for anybody who is thinking of studying for a university degree and would like to... Try: English: skills for learning now
This unit explains the function of the cytoskeleton and its role in controlling...
This unit explains the function of the cytoskeleton and its role in controlling transport of vesicles between different subcellular compartments.
By the end of this unit you should be able to:
- define and use each of the terms printed in bold in the text.
- describe the characteristics of different intracellular compartments with respect to their structure, location and composition within a mammalian cell;
- describe the traffic pathways between the endoplasmic reticulum, the Golgi apparatus, the endosomal compartments, and the basolateral and apical regions of the plasma membrane;
- give examples of regulated and unregulated secretion, the mechanisms controlling the processes, and their functional significance;
- give examples of endocytosis, the mechanisms involved and their functional significance;
- describe the components of the cytoskeleton and their role in intracellular transport;
- describe the main classes of motor protein and their functions within the cell;
- understand the role of compartmentalisation in organising different intracellular regions for distinct biochemical interactions and cell functions, which are specific for each type of cell;
- design and interpret the results of an experiment to investigate the subcellular localisation of a receptor protein, based on the technique of immuno-electron microscopy.
- Current section: Introduction
- Learning outcomes
- 1 The cytoskeleton
- 2 Cellular compartments and traffic
- 3 Trafficking vesicles
- 4 Signals for compartmentalisation
- 5 The cytoskeleton and motor proteins
- 6 Endocytic pathways
- 7 Exocytosis
- Next steps
Study this free course
Enrol to access the full course, get recognition for the skills you learn, track your progress and on completion gain a statement of participation to demonstrate your learning to others. Make your learning visible!
The cytoskeleton is of fundamental importance to a cell, and the development of different elements of the cytoskeleton were key steps in the evolution of eukaryotic cells. The cytoskeleton controls cell shape and allows cell movement; it is required for many aspects of intracellular trafficking of vesicles and organelles, and it is involved in cell division. Because of its important role in facilitating the movement of vesicles between compartments, but a basic understanding of how the cytoskeleton works is equally important for cell division and cell migration.
This unit is an adapted extract from the Open University course S377.
Copyright & revisions
Originally published: Monday, 8th July 2013
Last updated on: Monday, 8th July 2013
- Creative-Commons: The Open University is proud to release this free course under a Creative Commons licence. However, any third-party materials featured within it are used with permission and are not ours to give away. These materials are not subject to the Creative Commons licence. See terms and conditions. Full details can be found in the Acknowledgements section.
- This site has Copy Reuse Tracking enabled - see our FAQs for more information.
If you enjoyed this, why not follow a feed to find out when we have new things like it? Choose an RSS feed from the list below. (Don't know what to do with RSS feeds?)
Remember, you can also make your own, personal feed by combining tags from around OpenLearn.