from The Open University
Alternatively you can skip the navigation by pressing 'Enter'.
Life In Cold Blood: Sophisticated SerpentsSunday, 30th August 2015 08:00 - YesterdayThey get a bad rap in the Bible, but snakes are really quite wonderful Read more: Life In Cold Blood: Sophisticated Serpents
Life In Cold Blood: Sophisticated SerpentsSunday, 30th August 2015 13:00 - Yesterday
The world’s busiest railway 2015 – Mumbai Railway: Episode 1Sunday, 30th August 2015 18:00 - BBC Two
More or Less: Chinese market crash, e-cigarettes and runnersSunday, 30th August 2015 20:00 - BBC Radio 4
More or Less: Chinese market crash, e-cigarettes and runnersAvailable until Sunday, 27th September 2015 16:55More or Less investigates the Chinese market crash, e-cigarettes, engineering and how sprinters run so fast. Read more: More or Less: Chinese market crash, e-cigarettes and runners
The world’s busiest railway 2015 – Mumbai Railway: Episode 1Available until Tuesday, 29th September 2015 19:00
Are our kids tough enough? Chinese school: Episode TwoAvailable until Monday, 28th September 2015 01:55
Canals: The Making of a Nation: The Boat PeopleAvailable until Sunday, 27th September 2015 20:00
OpenLearn Live: August Bank Holiday Special 2015Not so much live, but with a great collection of free courses, things to watch and listen to, and... Read more: OpenLearn Live: August Bank Holiday Special 2015
Are our kids tough enough? Chinese schoolIn a unique experiment, five teachers from China take over the education of 50 teenagers in a... Read more: Are our kids tough enough? Chinese school
Challenges in advanced management accountingThis free course, Challenges in advanced management accounting, focuses on strategic management... Try: Challenges in advanced management accounting now
Forensic psychologyDiscover how psychology can help obtain evidence from eyewitnesses in police investigations and... Try: Forensic psychology now
This unit explains the function of the cytoskeleton and its role in controlling...
This unit explains the function of the cytoskeleton and its role in controlling transport of vesicles between different subcellular compartments.
By the end of this unit you should be able to:
- define and use each of the terms printed in bold in the text.
- describe the characteristics of different intracellular compartments with respect to their structure, location and composition within a mammalian cell;
- describe the traffic pathways between the endoplasmic reticulum, the Golgi apparatus, the endosomal compartments, and the basolateral and apical regions of the plasma membrane;
- give examples of regulated and unregulated secretion, the mechanisms controlling the processes, and their functional significance;
- give examples of endocytosis, the mechanisms involved and their functional significance;
- describe the components of the cytoskeleton and their role in intracellular transport;
- describe the main classes of motor protein and their functions within the cell;
- understand the role of compartmentalisation in organising different intracellular regions for distinct biochemical interactions and cell functions, which are specific for each type of cell;
- design and interpret the results of an experiment to investigate the subcellular localisation of a receptor protein, based on the technique of immuno-electron microscopy.
- Current section: Introduction
- Learning outcomes
- 1 The cytoskeleton
- 2 Cellular compartments and traffic
- 3 Trafficking vesicles
- 4 Signals for compartmentalisation
- 5 The cytoskeleton and motor proteins
- 6 Endocytic pathways
- 7 Exocytosis
- Next steps
Study this free course
Enrol to access the full course, get recognition for the skills you learn and track your progress. Make your learning visible!
The cytoskeleton is of fundamental importance to a cell, and the development of different elements of the cytoskeleton were key steps in the evolution of eukaryotic cells. The cytoskeleton controls cell shape and allows cell movement; it is required for many aspects of intracellular trafficking of vesicles and organelles, and it is involved in cell division. Because of its important role in facilitating the movement of vesicles between compartments, but a basic understanding of how the cytoskeleton works is equally important for cell division and cell migration.
This unit is an adapted extract from the Open University course S377.
Copyright & revisions
Originally published: Monday, 8th July 2013
Last updated on: Monday, 8th July 2013
- Creative-Commons: The Open University is proud to release this free course under a Creative Commons licence. However, any third-party materials featured within it are used with permission and are not ours to give away. These materials are not subject to the Creative Commons licence. See terms and conditions. Full details can be found in the Acknowledgements section.
- This site has Copy Reuse Tracking enabled - see our FAQs for more information.
If you enjoyed this, why not follow a feed to find out when we have new things like it? Choose an RSS feed from the list below. (Don't know what to do with RSS feeds?)
Remember, you can also make your own, personal feed by combining tags from around OpenLearn.