Nucleic acids and chromatin
Nucleic acids and chromatin

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Nucleic acids and chromatin


The content acknowledged below is Proprietary (see terms and conditions) and is used under licence.

Grateful acknowledgement is made to the following sources for permission to reproduce material in this unit:

Figure 1a: Courtesy Robert Saunders;

Figure 1c: Mark Hirst and David Shuker/ Open University;

Figure 1d: Dr Thomas Broker;

Figure 1e: Dr George Palade;

Figure 1f: Fedoroff and Botstein (1992) ‘The plural of heterochromatin’, The Dynamic Genome, Cold Spring Harbor Laboratory;

Figures 7a, d, 8a, b, 33b: Mark Hirst/Open University;

Figure 8c: Ruth Akhter/Open University;

Figure 14: Teicher, B. A. (ed.) (1997) ‘DNA topoisomerase II inhibitors’, Cancer Therapeutics: Experimental and Clinical Agents, Humana Press Inc.;

Figure 16: Courtesy Peter Lansdorp, Terry Fox Laboratory, B. C. Cancer Research Center, UBC, Vancouver, Canada;

Figure 17c: Brown, V. P. et al. (2001) ‘Microarray identification of FMRP-associated brain mRNAs …’, Cell, 107, Cell Press;

Figure 18a, c: Rich, A. et al. (1973) ‘Three-dimensional structure of yeast Phe tRNA’, Science, 179, copyright © American Association for the Advancement of Science; Ladner, J. et al. (1975) ‘Structure for yeast Phe tRNA’, Proceedings of the National Academy of Sciences, 12, National Academy of Sciences, reprinted with permission from Nature, 250, copyright © 1974;

Figures 18b, 19: Moss, E. G. ‘MicroRNAs: hidden in the genome’, Current Biology, 12, copyright © 2000 Elsevier;

Figure 23c: Bulyk, M. L. et al. (2001) ‘Exploring the DNA-binding specifications of zinc fingers with DNA microarrays’, Proceedings of the National Academy of Sciences, 98, June 19, copyright © 2001 National Academy of Sciences;

Figure 29b: Photograph kindly provided by Barbara Hamkalo;

Figure 29c: Wolffe, A. (1995) Chromatin Structure and Function, 2nd edn, copyright © 1995 Elsevier;

Figure 34: Bulger, M. et al. (2002) ‘ChIPs of the  -globin locus …’, Current Opinion in Genetics and Development, 12, copyright © 2002 Elsevier;

Figure 36: Boggs, B. A. et al. (2002) ‘Differentially methylated forms of histone H3 …’, Nature Genetics, 30, January, Nature Publishing Co.;

Figure 37: Grewal, S. and Elgin S. C. R. (2002) ‘Heterochromatin: new possibilities for the inheritance of structure’, Current Opinion in Genetics and Development, 12, copyright © 2002 Elsevier;

Figure 38: Pereira, S. L. et al. (1997) ‘Archaeal nucleosomes’, Proceedings of the National Academy of Sciences, 94, Nov., copyright © 1997 National Academy of Sciences;

Figure 41: Courtesy Joseph G. Gall;

Figure 42a: Boyle, S. et al. (2001) ‘The spatial organization of human chromosomes …’, Human Molecular Genetics, 10(3), by permission of Oxford University Press;

Figure 42b: Lemke, J. et al. (2002) ‘The DNA-based structure of human chromosome 5 in interphase’, American Journal of Human Genetics, 71, The American Society of Human Genetics;

Figure 43: Adapted from Purves, W. K. et al. (1998) Life, the Science of Biology, 5th edn, Sinauer Associates Inc.

All other materials included in this unit are derived from content originated at the Open University.

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