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The Secret History of Our Streets - London: Arnold CircusThursday, 8th December 2016 00:45 - BBC FourThe sixth episode features Arnold Circus, in the East End and the story of a Victorian social experiment that changed... Read more: The Secret History of Our Streets - London: Arnold Circus
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The Secret History of Our Streets - London: Arnold CircusAvailable until Saturday, 7th January 2017 01:45The sixth episode features Arnold Circus, in the East End and the story of a Victorian social experiment that changed... Read more: The Secret History of Our Streets - London: Arnold Circus
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This free course, What do genes do? explores how information contained in DNA is used, explaining the flow of information from DNA to RNA to protein. Also introduced are the concepts of transcription (as occurs between DNA and RNA) and translation.
After studying this course, you should be able to:
- understand how the linear sequence of DNA within a gene is related to the linear sequence of amino acids of a protein
- understand how the information in DNA is carried via RNA to make a protein
- understand how RNA is synthesised from DNA by the process of transcription
- understand where the processes of transcription and translation occur within the cell.
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5 Where does transcription occur in the cell?
Up to now we have described the processes of transcription without considering where each occurs within the cell.
Given that transcription — the production of mRNA — requires a DNA template, where do you think this process occurs in the cell?
It must occur in the nucleus where the DNA in the cell is located.
However, once mRNA is produced, it leaves the nucleus and protein synthesis – translation – occurs in the cytoplasm. Thus transcription and translation are separated both in space within the cell and in time, in that one occurs after the other, as shown schematically in Figure 11.8. Thus the role of mRNA is to carry a coded message from the nucleus where the information is stored, to the cytoplasm where the coded message is translated into a specific protein; hence it’s name – messenger RNA.
Translation occurs at particular sites within the cytoplasm; it occurs on ribosomes. Ribosomes are large aggregates of proteins and ribosomal RNA (rRNA). Hence three types of RNA are involved in the process of translation but only one of them, mRNA, codes for proteins.
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This free course includes adapted extracts from an Open University course which is no longer available to new students. If you found this interesting you could explore more free Biology courses or view the range of currently available OU Biology courses.
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Originally published: Wednesday, 2nd March 2016
Last updated on: Wednesday, 2nd March 2016
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