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Contents
- Introduction
- Learning outcomes
- 1 Understanding the role of stress
- 2 Stress and the brain
- 3 The life cycle model of stress
- 4 Insights from antidepressants
- 4.1 The monoamine hypothesis of mood disorders
- 4.2 Evidence for the monoamine hypothesis
- 4.3 Tryptophan depletion experiments
- 4.4 The neurotrophic hypothesis of mood disorders
- 4.5 Depression and levels of BDNF
- 4.6 Stress, depression and neurogenesis in the hippocampus
- 4.7 Antidepressants, BDNF levels and neurogenesis in the hippocampus
- 5 The network hypothesis of mood disorders
- 6 Genes and environment: bringing it all together
- Conclusion
- Keep on learning
- References
- Acknowledgements
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