This figure comprises a bar graph showing cefepime resistance of E. coli isolates in the UK between 2004 and 2016. The horizontal axis is labelled year and is marked from 2004 to 2016 in 1-year intervals except between 2004 and 2007 where no data is included. The vertical axis is labelled resistant (%) and is marked from 0 to 100 in intervals of 10. The blue bars represent E. coli isolates that contain ESBLs. The red bars represent E. coli isolates that do not contain ESBLs. The blue bars are much larger than the red bars in all years. The blue bars range from 50% in 2004 and 2013 to 100% in 2007 and 2008. The red bars never exceed 10%.