This figure comprises a line graph showing the frequency of ESBL-positive E. coli isolates in the UK between 2001 and 2016. The horizontal axis is labelled year and is marked from 2000 to 2016 in 2-year intervals. The vertical axis is labelled ESBL-positive isolates (%) and is marked from 0 to 14 in intervals of 2. The line crosses the horizontal axis at 2001 and slopes upwards to a peak at 13% in 2006. It then slopes downwards to 6% in 2011 before slopping upwards again to 12% in 2013. It ends at 10% in 2016.