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Figure 44 Space-filling representation of bovine carboxypeptidase A (a) without substrate bound (pdb file 2ctb) and (b) with substrate (glycyltyrosine, shown in white) bound (pdb file 3cpa). (c) A close-up view of the substrate binding site with the polypeptide backbone shown in ribbon format, coloured as in (b). The zinc ion is shown in pink and key residues involved in coordinating the zinc ion are highlighted in space-filling format as follows: Glu 72, red; His 69, yellow; His 196, orange.

 6.4 Carboxypeptidase A