The science of nutrition and healthy eating
The science of nutrition and healthy eating

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The science of nutrition and healthy eating

1.3 Anaphylaxis

In 1902, the phenomenon of anaphylaxis was first described in the medical literature. Researchers noticed an unusual effect in dogs when immunising them with jellyfish toxin. The intention was to protect the dogs but instead it caused a fatal or near-fatal response. This is where the word ‘anaphylaxis’ was created, from the Greek words ana (meaning against) and phylaxis (immunity or protection).

Watch the following video from the British Red Cross.

Download this video clip.Video player: snhe_1_week7_vid1.mp4
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Transcript

[MUSIC PLAYING]
FRIEND
Hmm, so good. Cheers. This looks good.
DUNCAN
As I was saying, we’re off to Spain for a fortnight.
FRIEND
All right.
DUNCAN
This time next month, hey, darling? Mm.
FRIEND
That’s lovely. I’ve never been to Spain.
DUNCAN
Oh, we’ve been a few times.
FRIEND
All right. OK. You flying?
DUNCAN
We’re flying from Manchester this time.
FRIEND
OK. Yeah.
DUNCAN
I’m really looking forward to it.
FRIEND
So what are you going to be doing?
WOMAN
Duncan?
DUNCAN
Yes?
WOMAN
I think there’s nuts in this. My throat’s closing up.
DUNCAN
You phone for an ambulance.
WOMAN
I can’t breathe proper.
DUNCAN
Where’s your injector, your auto-injector?
WOMAN
In my bag.
DUNCAN
Just tell them it’s anaphylaxis.
FRIEND
Hello? Hello? Yes. Can I have an ambulance, please?
Yes. It’s my friend. She’s having an allergic reaction. Yeah.
Yes, it;s anaphylaxis. Yeah, we’re at the Ocean Restaurant.
DUNCAN
There you are.
FRIEND
Yeah. Yeah.
That’s right, Oakley. 45 Glover Street. That’s right. Yeah.
[MUSIC PLAYING]
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What is happening in the body to give such a reaction?

When the body is first exposed to the food that you may be allergic to (the allergen), an antibody (IgE) specific to the allergen is produced. When the body is exposed to that allergen again, the allergen-specific IgE causes the cells to release inflammatory chemicals such as histamine. This surge in histamine then affects different parts of the body, causing anaphylaxis (Figure 2) and potentially anaphylactic shock, which is a life-threatening condition and requires immediate attention.

Described image
Figure 2 Signs and symptoms of anaphylaxis

You saw in the video that the treatment is an auto-injector pen filled with the hormone epinephrine (also calledadrenalin) in an EpiPen®. This relieves the symptoms but it is essential to seek medical advice also. This is because a single dose may not be enough and any further doses must be administered medically.

SNHE_1

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