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This figure shows a picture of the protein structure of a CTX-M-type ESBL. This structure is comprised of beta structures shown in yellow, alpha helices shown in pink and loop regions shown in white. The β-lactam binding site is indicated by the blue arrow. The amino acid mutation that increases the ceftazidimase activity of CTX-M is indicated by a blue star.

 4.3 Mutations in CTX-M-type ESBLs