Cell signalling
Cell signalling

This free course is available to start right now. Review the full course description and key learning outcomes and create an account and enrol if you want a free statement of participation.

Free course

Cell signalling

3.4.3 Cyclic GMP

Cyclic GMP (cGMP) is a second messenger with many similarities to cAMP. It is synthesized from GTP by guanylyl cyclase, and degraded to 5´- GMP by cyclic GMP phosphodiesterases. Some of the targets of cGMP are analogous to those of cAMP: cGMP-dependent protein kinase (PKG), and cGMP-gated Na+ ion channels.

  • We have already discussed a type of receptor that employs cGMP for signal transfer. What type of receptor is it?

  • Receptors with intrinsic enzymatic activity with an intracellular guanylyl cyclase catalytic domain (Figure 23a).

S377_4

Take your learning further

Making the decision to study can be a big step, which is why you'll want a trusted University. The Open University has 50 years’ experience delivering flexible learning and 170,000 students are studying with us right now. Take a look at all Open University courses.

If you are new to university level study, find out more about the types of qualifications we offer, including our entry level Access courses and Certificates.

Not ready for University study then browse over 900 free courses on OpenLearn and sign up to our newsletter to hear about new free courses as they are released.

Every year, thousands of students decide to study with The Open University. With over 120 qualifications, we’ve got the right course for you.

Request an Open University prospectus