Nucleic acids and chromatin
Nucleic acids and chromatin

Start this free course now. Just create an account and sign in. Enrol and complete the course for a free statement of participation or digital badge if available.

Free course

Nucleic acids and chromatin

2.2 General features of higher-order nucleic acid structure

Polynucleotide chains are intrinsically flexible molecules and have the potential to form many different higher-order structures. Their flexibility derives from rotation around bonds in the sugar-phosphate backbone (Figure 3b). In vivo, the structures that form are obviously determined by both the proteins that synthesise the nucleic acid chains (polymerases) and the ancillary proteins that bind to and modify them. We will discuss these aspects of structure later in this unit. What drives the formation of these structures are the properties of the component nucleotides and the interactions between them in the form of base pairing and base stacking.

S377_1

Take your learning further371

Making the decision to study can be a big step, which is why you'll want a trusted University. The Open University has 50 years’ experience delivering flexible learning and 170,000 students are studying with us right now. Take a look at all Open University courses372.

If you are new to university level study, we offer two introductory routes to our qualifications. Find out Where to take your learning next?373 You could either choose to start with an Access courses374or an open box module, which allows you to count your previous learning towards an Open University qualification.

Not ready for University study then browse over 1000 free courses on OpenLearn375 and sign up to our newsletter376 to hear about new free courses as they are released.

Every year, thousands of students decide to study with The Open University. With over 120 qualifications, we’ve got the right course for you.

Request an Open University prospectus371