Nucleic acids and chromatin
Nucleic acids and chromatin

Start this free course now. Just create an account and sign in. Enrol and complete the course for a free statement of participation or digital badge if available.

Free course

Nucleic acids and chromatin

Summary of Section 2

  1. Nucleic acids are intrinsically highly flexible molecules.

  2. The chemical properties of nucleic acid components are primary determinants in structure formation.

  3. The formation of nucleic acid structures is driven by base pairing and stacking interactions between the hydrophobic bases. In DNA, these interactions drive the formation of the double helix, whose structure is maintained under torsional stress by twisting. RNA secondary structure is driven by maximal base-pairing rules.

  4. The five common bases found in nucleic acids can be modified after synthesis.

  5. Base pairing is exploited in the laboratory in many techniques that utilise strand annealing (hybridisation) between a labelled nucleic acid and a target polynucleotide.


Take your learning further

Making the decision to study can be a big step, which is why you'll want a trusted University. The Open University has 50 years’ experience delivering flexible learning and 170,000 students are studying with us right now. Take a look at all Open University courses.

If you are new to University-level study, we offer two introductory routes to our qualifications. You could either choose to start with an Access module, or a module which allows you to count your previous learning towards an Open University qualification. Read our guide on Where to take your learning next for more information.

Not ready for formal University study? Then browse over 1000 free courses on OpenLearn and sign up to our newsletter to hear about new free courses as they are released.

Every year, thousands of students decide to study with The Open University. With over 120 qualifications, we’ve got the right course for you.

Request an Open University prospectus371