◄Previous: 7 Summary

# References

Alenghat, T., Osborne, L.C., Saenz, S.A., Kobuley, D., Ziegler, C.G.K., Mullican, S.E., Choi, I., Grunberg, S., et al. (2013) ‘Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis’, Nature, 504, pp. 153–157. Available at: https://doi.org/10.1038/nature12687

Álvarez-Herms, J., González, A., Corbi, F., Odriozola, I. and Odriozola, A. (2023) ‘Possible relationship between the gut leaky syndrome and musculoskeletal injuries: the important role of gut microbiota as indirect modulator’, AIMS Public Health, 10(3), pp. 710–738. Available at: https://doi.org/10.3934/publichealth.2023049

Arumugam, M., Raes, J., Pelletier, E., le Paslier, D., Yamada, T., Mende, D.R., Fernandes, G.R., Tap, J., et al. (2011) ‘Enterotypes of the human gut microbiome’, Nature, 473, pp. 174–180. Available at: https://doi.org/10.1038/nature09944

Aune, D., Chan, D.S.M., Lau, R., Vieira, R., Greenwood, D.C., Kampman, E. and Norat, T. (2011) ‘Dietary fibre, whole grains, and risk of colorectal cancer: systematic review and dose-response meta-analysis of prospective studies’, British Medical Journal, 343, d6617. Available at: https://doi.org/10.1136/bmj.d6617

Bastiaanssen, T.F.S., Cussotto, S., Claesson, M.J., Clarke, G., Dinan, T.G. and Cryan, J.F. (2020) ‘Gutted! Unraveling the role of the microbiome in major depressive disorder’, Harvard Review of Psychiatry, 28(1), pp. 26–39. Available at: https://doi.org/10.1097/hrp.0000000000000243

Bibbò, S., Fusco, S., Ianiro, G., Settanni, C.R., Ferrarese, D., Grassi, C., Cammarota, G. and Gasbarrini, A. (2022) ‘Gut microbiota in anxiety and depression: Pathogenesis and therapeutics’, Frontiers in Gastroenterology, 1. Available at: https://doi.org/10.3389/fgstr.2022.1019578

Boccuto, L., Tack, J., Ianiro, G., Abenavoli, L. and Scarpellini, E. (2023) ‘Human Genes Involved in the Interaction between Host and Gut Microbiome: Regulation and Pathogenic Mechanisms’, Genes (Basel), 14(4), p. 857. Available at: https://doi.org/10.3390/genes14040857

Bolte, L.A., Vila, A.V., Imhann, F., Collij, V., Gacesa, R., Peters, V., Wijmenga, C. and Kurilshikov, A. (2021) ‘Long-term dietary patterns are associated with pro-inflammatory and anti-inflammatory features of the gut microbiome’, Gut, 70(7), pp. 1287–1298. Available at: https://doi.org/10.1136/gutjnl-2020-322670

Cancer Research UK (2022) Wholegrains, fibre and cancer risk. Available at: https://www.cancerresearchuk.org/about-cancer/causes-of-cancer/diet-and-cancer/wholegrains-fibre-and-cancer-risk (Accessed: 7 March 2025).

Chen, Y., Xu, J. and Chen, Y. (2021) ‘Regulation of neurotransmitters by the gut microbiota and effects on cognition in neurological disorders’, Nutrients, 13(6), p. 2099. Available at: https://doi.org/10.3390/nu13062099

Cooke, M.B., Catchlove, S. and Tooley, K.L. (2022) ‘Examining the influence of the human gut microbiota on cognition and stress: a systematic review of the literature’, Nutrients, 14(21), p. 4623. Available at: https://doi.org/10.3390/nu14214623

Damman, C. (2024) ‘Athletes looking for a competitive edge may find it within their gut microbiome’, The Conversation, 23 July. Available at: https://theconversation.com/athletes-looking-for-a-competitive-edge-may-find-it-within-their-gut-microbiome-234979 (Accessed: 10 June 2025).

Dohnalová, L., Lundgren, P., Carty, J.R.E., Goldstein, N., Wenski, S.L., Nanudorn, P., Thiengmag, S., Huang, K-P., et al. (2022) ‘A microbiome-dependent gut–brain pathway regulates motivation for exercise’, Nature, 612, pp. 739–747. Available at: https://doi.org/10.1038/s41586-022-05525-z

Ghosh, T.S., Shanahan, F. and O’Toole, P.W. (2022) ‘The gut microbiome as a modulator of healthy ageing’, Nature Reviews Gastroenterology & Hepatology, 19, pp. 565–584. Available at: https://doi.org/10.1038/s41575-022-00605-x

Gupta, S., Allen-Vercoe, E. and Petrof, E.O. (2016) ‘Fecal microbiota transplantation: in perspective’, Therapeutic Advances in Gastroenterology, 9(2), pp. 229–39. Available at: https://doi.org/10.1177/1756283X15607414

HMPDACC (n.d.) NIH Human Microbiome Project. Available at: https://www.hmpdacc.org (Accessed 7 March 2025).

Jabr, F. (2017) ‘Do probiotics really work?’, Scientific American, 1 July. Available at: https://www.scientificamerican.com/article/do-probiotics-really-work (Accessed: 7 March 2025).

Johns Hopkins (n.d.) Fecal Transplant. Available at: https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/fecal-transplant (Accessed: 10 June 2025).

Kalantar-Zadeh, K., Berean, K.J., Burgell, R.E., Muir, J.G. and Gibson, P.R. (2019) ‘Intestinal gases: influence on gut disorders and the role of dietary manipulations’, Nature Reviews Gastroenterology & Hepatology, 16, pp. 733–747. Available at: https://doi.org/10.1038/s41575-019-0193-z

Kidney Research UK (2023) Kidney disease: A UK public health emergency. Available at: https://www.kidneyresearchuk.org/about-us/policy/health-economics-report/ (Accessed: 10 June 2025).

Kim, G., Lee, K. and Shim, J.O. (2023) ‘Gut Bacterial Dysbiosis in Irritable Bowel Syndrome: a Case-Control Study and a Cross-Cohort Analysis Using Publicly Available Data Sets’, Microbiology Spectrum, 11, e02125-22. Available at: https://doi.org/10.1128/spectrum.02125-22

Li, P.K-T., Chan, G.C-K., Chen, J., Chen, H-C., Cheng, Y-L., Fan, S.L-S, He, J.C., Hu, W., et al. (2021) ‘Tackling dialysis burden around the world: A global challenge’, Kidney Diseases, 7(3), pp. 167–175. Available at: https://doi.org/10.1159/000515541

Limketkai, B.N., Akobeng, A.K., Gordon, M. and Adepoju, A.A. (2020) ‘Probiotics for induction of remission in Crohn’s disease’, The Cochrane Database of Systematic Reviews, 7(7), CD006634. Available at: https://doi.org/10.1002/14651858.CD006634.pub3

Limketkai, B.N., Hamideh, M., Shah, R., Sauk, J.S. and Jaffe, N. (2022) ‘Dietary Patterns and Their Association With Symptoms Activity in Inflammatory Bowel Diseases’, Inflammatory Bowel Diseases, 28(11), pp. 1627–1636. Available at: https://doi.org/10.1093/ibd/izab335

Mailing, L.J., Allen, J.M., Buford, T.W., Fields, C.J. and Woods, J.A. (2019) ‘Exercise and the Gut Microbiome: A Review of the Evidence, Potential Mechanisms, and Implications for Human Health’, Exercise and Sport Sciences Reviews, 47(2), pp. 75–85. Available at: https://doi.org/10.1249/JES.0000000000000183

Menees, S. and Chey, W. (2018) ‘The gut microbiome and irritable bowel syndrome’, F1000Research, 7(F1000 Faculty Rev), 1029. Available at: https://doi.org/10.12688/f1000research.14592.1

Mohajeri, M.H., Brummer, R.J.M., Rastall, R.A., Weersma, R.K., Harmsen, H.J.M., Faas, M. and Eggersdorfer, M. (2018) ‘The role of the microbiome for human health: from basic science to clinical applications’, European Journal of Nutrition, 57, pp. 1–14. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC5962619/

Monda, V., Villano, I., Messina, A., Valenzano, A., Esposito, T., Moscatelli, F., Viggiano, A., Cibelli, G., et al. (2017) ‘Exercise Modifies the Gut Microbiota with Positive Health Effects’, Oxidative Medicine and Cellular Longevity, 2017, 3831972. Available at: https://doi.org/10.1155/2017/3831972

NHS (2022) Probiotics. Available at: https://www.nhs.uk/conditions/probiotics (Accessed: 7 March 2025).

Peters, B.A., Santoro, N., Kaplan, R.C. and Qibin, Q. (2022) ‘Spotlight on the gut microbiome in menopause: Current insights’, International Journal of Women’s Health, 14, pp. 1059–1072. Available at: https://doi.org/10.2147/IJWH.S340491

Roswall, J., Olsson, L.M., Kovatcheva-Datchary, P., Nilsson, S., Tremaroli, V., Simon, M.-C., Kiilerich, P., Akrami, R., et al. (2021) ‘Developmental trajectory of the healthy human gut microbiota during the first 5 years of life’, Cell Host & Microbe, 9(5), pp. 765–776. Available at: https://doi.org/10.1016/j.chom.2021.02.021

Sadagopan, A., Mahmoud, A., Begg, M., Tarhuni, M., Fotso, M., Gonzalez, N.A., Sanivarapu, R.R., Osman, U., et al. (2023) ‘Understanding the Role of the Gut Microbiome in Diabetes and Therapeutics Targeting Leaky Gut: A Systematic Review’, Cureus, 15(7), e41559. Available at: https://doi.org/10.7759/cureus.41559

Salvadori, M. and Rosso, G. (2024) ‘Update on the gut microbiome in health and diseases’, World Journal of Methodology, 14(1), 89196. Available at: https://doi.org/10.5662/wjm.v14.i1.89196

Sanders, D.J., Inniss, S., Sebepos-Rogers, G., Rahman, F.Z. and Smith, A.M. (2021) ‘The role of the microbiome in gastrointestinal inflammation’, Bioscience Reports, 41(6), BSR20203850. Available at: https://doi.org/10.1042/BSR20203850

Shi, Z. (2019) ‘Gut microbiota: An important link between Western diet and chronic diseases’, Nutrients, 11(10), pp. 2287.

Silva, Y.P., Bernardi, A. and Frozza, R.L. (2020) ‘The role of short-chain fatty acids from gut microbiota in gut-brain communication’, Frontiers in Endocrinology, 11. Available at: https://doi.org/10.3389/fendo.2020.00025

Spragge, F., Bakkeren, E., Jahn, M.T., Araujo, E.B.N., Pearson, C.F., Wang, X., Pankhurst, L., Cunrath, O. and Foster, K.R. (2023) ‘Microbiome diversity protects against pathogens by nutrient blocking’, Science, 382, eadj3502(2023). Available at: https://doi.org/10.1126/science.adj3502

Stasi, C., Sadalla, S. and Milani, S. (2019) ‘The relationship between the serotonin metabolism, gut-microbiota and the gut-brain axis’, Current Drug Metabolism, 20(8), pp. 646–655. Available at: https://doi.org/10.2174/1389200220666190725115503

Stojanov, S., Berlec, A. and Štrukelj, B. (2020) ‘The influence of probiotics on the Firmicutes/Bacteroidetes ratio in the treatment of obesity and inflammatory bowel disease’, Microorganisms, 8(11), p. 1715. Available at: https://doi.org/10.3390/microorganisms8111715

Suzuki, T.A. and Worobey, M. (2014) ‘Geographical variation of human gut microbial composition’, Biology Letters, 10, 20131037. Available at: https://doi.org/10.1098/rsbl.2013.1037

Weersma, R.K., Zhernakova, A. and Fu, J. (2020) ‘Interaction between drugs and the gut microbiome’, Gut, 69, pp. 1510–1519.

Wilmanski, T., Diener, C., Rappaport, N., Patwardhan, S., Wiedrick, J., Lapidus, J., Earls, J.C., Zimmer, A., et al. (2021) ‘Gut microbiome pattern reflects healthy ageing and predicts survival in humans’, Nature Metabolism, 3(2), pp. 274–286. Available at: https://doi.org/10.1038/s42255-021-00348-0

Wong, C.C. and Yu, J. (2023) ‘Gut microbiota in colorectal cancer development and therapy’, Nature Reviews Clinical Oncology, 20, pp. 429–452. Available at: https://doi.org/10.1038/s41571-023-00766-x

World Health Organization (2023) Colorectal cancer. Available at: https://www.who.int/news-room/fact-sheets/detail/colorectal-cancer (Accessed: 10 June 2025).

Xiong, R.G., Li, J., Cheng, J., Zhou, D.D., Wu, S.X., Huang, S.Y., Saimaiti, A., Yang, Z.J., et al. (2023) ‘The Role of Gut Microbiota in Anxiety, Depression, and Other Mental Disorders as Well as the Protective Effects of Dietary Components’, Nutrients, 15(14), p. 3258. Available at: https://doi.org/10.3390/nu15143258

Yang, B., Wei, J., Ju, P. and Chen, J. (2019) ‘Effects of regulating intestinal microbiota on anxiety symptoms: a systematic review’, General Psychiatry, 32(2), e100056. Available at: https://doi.org/10.1136/gpsych-2019-100056

Yeoh, Y.K., Zuo, T., Lui, G.C., Zhang, F., Liu, Q., Li, A.Y.L., Chung, A.C.K., Cheung, C.P., et al. (2021) ‘Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19’, Gut, 70, pp. 698–706.

Zhang, P. (2022) ‘Influence of Foods and Nutrition on the Gut Microbiome and Implications for Intestinal Health’, International Journal of Molecular Sciences, 23(17), p. 9588. Available at: https://doi.org/10.3390/ijms23179588

Zhao, Q., Chen, Y., Huang, W., Zhou, H. and Zhang, W. (2023) ‘Drug-microbiota interactions: an emerging priority for precision medicine’, Signal Transduction and Targeted Therapy, 8, p. 386. Available at: https://doi.org/10.1038/s41392-023-01619-w

Zhu, F., Tu, H. and Chen, T. (2022) ‘The microbiota-gut-brain axis in depression: the potential pathophysiological mechanisms and microbiota combined antidepression effect’, Nutrients, 14(10), p. 2081. Available at: https://doi.org/10.3390/nu14102081

Zinöcker, M.K. and Lindseth, I.A. (2018) ‘The Western Diet-Microbiome-Host Interaction and Its Role in Metabolic Disease’, Nutrients, 10(3), p. 365. Available at: https://doi.org/10.3390/nu10030365

◄Contents►Next: Acknowledgements

OpenLearn - The gut microbiome – balancing the body
Except for third party materials and otherwise, this content is made available under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Licence, full copyright detail can be found in the acknowledgements section. Please see full copyright statement for details.