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Most people diagnosed with MND have the sporadic form, which is not inherited. The causes are still being researched, but it’s believed that a combination of genetic, environmental, and lifestyle factors may be involved. A smaller proportion — about 5–10% — have inherited or familial MND, where a faulty gene is passed down through families.
MND can affect adults of any age and from all communities. However, it is most common in people aged 55–79. Onset below age 40 is uncommon, and onset under age 30 is extremely rare. MND affects slightly more men than women.