The Healthcare Cost and Utilization Project (HCUP) is a family of healthcare databases and related software tools and products developed through a Federal-State-Industry partnership and sponsored by the Agency for Healthcare Research and Quality (AHRQ). Among the open software they make available, we can highlight:

- Clinical Classification System (CCS) for ICD-9-CM and ICD-10-CM.

- Chronic Condition Indicator (CCI).

- Elixhauser Comorbidity Software.

This open software tools can be used for the management of clinical-administrative databases with research purposes.