4.3.4 Challenges of veterinary laboratories in LMIC constraints

Compared to human medicine, there are many fewer veterinary microbiology laboratories, and they are often underutilised in food animal disease investigations. In LMICs, the shortage of veterinary microbiology laboratories, skilled staff, access to veterinary services, and the high cost of testing are key challenges. Also, many of the farming enterprises in LMICs tend to be small-scale, low-input systems in remote locations, making sampling challenging both in taking samples and transporting them to the laboratory.

The diagnostic challenges faced by LMICs are well recognised. Global organisations, including WHO, OIE, and FAO, and international aid programmes such as the Fleming Fund (UK Aid) are partnering with other countries to build laboratory capacity and train staff in human and animal health laboratories.

Innovative approaches to disrupt the traditional microbiology laboratory model are being explored, such as telepathology, the use of algorithms to predict antimicrobial resistance, and rapid point-of-care tests. Many of the technologies being developed could take the laboratory into the community or to the site of sample collection. These new technologies offer great opportunities for diagnostics in LMICs provided they can be delivered with comparable accuracy to traditional methods, are low-cost, and able to overcome logistical challenges in the field (power, refrigeration, infrastructure, expertise, temperature, etc.).

Activity 10: Diagnostic stewardship

Timing: Allow about 10 minutes

What do you understand by the term ‘diagnostic stewardship’ and how does it address the misuse of antimicrobials?

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Discussion

Diagnostic stewardship essentially boils down to appropriate and timely use of diagnostic testing and reporting of results to guide therapeutic decisions. While it is borne out of human medicine, the principles can also be applied to veterinary medicine. Diagnostic stewardship is about obtaining the right test in the right patient to ensure the use of the right drug at the right time at the right dose for the right duration. By adopting these principles, antimicrobial use can be tailored to the infection and infection site to optimise use.

Of course, diagnostic stewardship can only be relevant to veterinary medicine when there are animal health or fish laboratories to support diagnostic testing. LMICs face particular challenges in fulfilling the principles of diagnostic stewardship, however global organisations, including WHO, OIE, and FAO, and international aid programmes such as the Fleming Fund (UK Aid) are partnering with a number of countries to build laboratory capacity and train staff in human and animal health laboratories.

4.3.3 Selective reporting of antibiotic susceptibility test (AST) results

5 International standards for prudent use of antimicrobials