The patient-centered model used in all healthcare projects needs to be redifined as patient empowerment and health self-control is getting more presence in the normal clinical  course of national healthcare systems.

The journal Open Access policies of PLoS Computational Biology are:

• paid open access: yes
• pre/post-print archiving: yes (pre- and post-print)
• embargo period: none, OA journal
• other restrictions/curiosities: authors retain copyright

PLoS Computational Biology is a RoMEO green journal.

Predatory publishing generally refers to the systematic for-profit publication of purportedly scholarly content (in journals and articles, monographs, books, or conference proceedings) in a deceptive or fraudulent way and without any regard for quality assurance. (Definition taken from COPE - Committee on Publication Ethics)

Further information

• Beall's List is a resource that helps you find out whether an OA journal that you plan to publish with is considered questionable or predatory: https://beallslist.net/
  

• More detailed information about the practice of predatory publishing and why it harms the reputation of scientists and Open Access Journals can be found in this discussion paper compiled by COPE: https://publicationethics.org/files/cope_dd_a4_pred_publishing_nov19_screenaw.pdf