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Understanding antibiotic resistance
Understanding antibiotic resistance

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Glossary


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P

pH indicator

A chemical compound that changes colour in solution, depending on the pH (acidity) of the solution they are mixed with.

phytochemical

Chemicals produced by plants. Many phytochemicals have antibacterial properties.

pilus

A thin hollow tube extension of the bacterial cell wall that connects bacteria and is involved in horizontal gene transfer via conjugation.


plasmid

A circular, non-chromosomal piece of DNA often carrying genes associated with a particular function, e.g. antibiotic resistance.

point-of-care (POC)

‘point-of-care is the specific location at which a patient is presenting with illness – this could be at home, or in a range of primary and secondary healthcare settings. Point-of-care diagnosis therefore takes place close to the patient, rather than at a physically removed central laboratory.’

Bailey, S. (2017) ‘What do we mean by point of care?’, Longitude Prize, 4 May 2017 [Blog]. Available at https://longitudeprize.org/blog-post/longitude-prize-what-do-we-mean-point-care (Accessed 28 February 2018).


polymerase chain reaction (PCR)

A laboratory technique that permits the analysis of short DNA sequences in a sample. PCR is used to amplify short sections of DNA for analysis.

porin

A transmembrane protein complex that allows the movement of small molecules across the bacterial outer membrane.


primary barrier

Sanitation and hygiene barrier that prevents initial contact with faeces. For example, providing people with access to flushing toilets.

primary metabolites

A type of metabolite directly involved in growth and development.

procalcitonin (PCT)

A precursor of the hormone calcitonin. Levels of PCT rise in patients with bacterial, but not viral, infections. Consequently, it can be used as a biomarker for bacterial infections.


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