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Understanding antibiotic resistance
Understanding antibiotic resistance

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Glossary


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P

prokaryotes

One of the two main categories of living things (the other is eukaryotes). Prokaryotic cells lack a nucleus, mitochondria and other membrane-bound organelles.  


prophylactically

Giving a medicine or treatment to a healthy individual in order to prevent disease occurring.

protein

A large molecule consisting of long chains of amino acids that performs many essential functions within cells.


public health

‘the art and science of preventing disease, prolonging life and promoting health through the organized efforts of society’ (Winslow, C.-E. A. (1920) ‘The untilled fields of public health’, Science, vol. 51, no. 1306, pp. 23–33).

Q

quorum sensing

The process by which bacteria communicate with each other. It allows bacteria to share information about cell density and change their behaviour accordingly. For example, at high cell density, Vibrio fischeri bacteria alter their behaviour to emit fluorescent light. At low cell density, the bacteria are not fluorescent.

R

rapid diagnostics

Medical diagnostic test that is quick and provides a rapid read-out that can be used to diagnose the patient.

reactive oxygen species (ROS)

Chemically reactive chemical compounds containing oxygen, for example hydrogen peroxide (H2O2). They can damage DNA and proteins.

replication

The synthesis of an exact copy of a DNA molecule.

resistance breakers

Drugs that do not kill bacteria themselves but, when co-administered with a failing antibiotic, can overcome resistance.

ribosome

A structure in the cell where proteins are made. Each ribosome consists of a large and a small subunit which have distinct roles in protein synthesis.


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