2,637 search results
Broken Hearts in Juvenile Dementia
Science, Maths & Technology

Broken Hearts in Juvenile Dementia

...changes in structure and calcium signalling inside cells. CLN3 is a rare disease which affects the eyes, brain and heart in humans, starting with eyesight deterioration around the age of 4-8 years. During their lifetime, patients experience worsening symptoms including seizures and a dementia-like deterioration. In their 20s they often develop heart problems and end of...
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Article 10 mins
What's the difference between a tall organisation and a flat organisation? The one-minute guide
Money & Business

What's the difference between a tall organisation and a flat organisation? The one-minute guide

...change more quickly. Managers may be forced to delegate if their span of control is enlarged. This can be motivating for those to whom work is delegated. On the other hand, career paths are less explicit: employees may have to look sideways or even outside the organisation for career development opportunities. What is delayering? In recent years, there has been a trend...
View article What's the difference between a tall organisation and a flat organisation? The one-minute guide
Article 1 min
Small Data: Star Wars release & broadcast dates
History & The Arts

Small Data: Star Wars release & broadcast dates

...changes in the entertainment industry?...[Line for the May 19th midnight showing of Star Wars: Episode I at the Stuart Theatre in Lincoln, Nebraska. May 18, 1999] A queue to see the 1999 Phantom Menace in Nebraska. But are Star Wars less patient now? You used to have to be quite patient as a British cinema fan - films would open in America, and then, eventually, they'd...
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Article 5 mins
Systems explained: What do we mean by feedback?
Money & Business

Systems explained: What do we mean by feedback?

...the greater the deviation from a healthy, less stressed frame of mind, the more difficult it becomes to correct it (through drugs, relaxation, change in lifestyle, etc). The danger of overcompensating in the other direction also increases through, for example, dependence on anti-depressant drugs or rash changes in other areas of life. [Feedback animation - boat and plane]...
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Article 5 mins
The genetics of autism
Health, Sports & Psychology

The genetics of autism

...changes that are not inherited from either parent, so-called de novo mutations, can also play a role in the development of autism. Researchers think that these de novo gene variants may play a more prominent role in those families where just one person has autism (also called sporadic autism). The occurrence of new genetic changes, not inherited from either parent, could...
View article The genetics of autism
Article 5 mins
Making Social Worlds
Society, Politics & Law

Making Social Worlds

...Changes in policy Sir Bernard Crick talking about the limitations of new citizenship policy. Migrant labour Sir Bernard Crick talking about changes in migrant worker recruitment. Freedom of speech The benefits of free speech in Britain and how it compares with other nations. Australian citizenship ceremony An Australian citizenship ceremony. The past politics of...
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Audio 55 mins
Buddhist Economics
Society, Politics & Law

Buddhist Economics

...change? Dr Mike Lucas assesses the changes to conventional accounting methods, and management teaching, that would be needed to establish a new business model based on Buddhist economics. Economics and accounting of the future? Alan Shipman and Dr Mike Lucas of The Open University discuss the problems of adopting new business models in a world where accounting and...
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Audio 44 mins
Roaring Twenties? Europe in the interwar period
History & The Arts

Roaring Twenties? Europe in the interwar period

...changing lifestyles of women and the increasingly interventionist approaches to managing the health and welfare of modern populations...While recognising the shadows cast by two world wars (one concluded and one imminent) over European society during the 1920s and 1930s, this free course, Roaring Twenties? Europe in the interwar period, demonstrates how a number of...
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Level 3: Advanced 14 hrs