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How can knowing how DNA repairs itself help defeat cancer?
Health, Sports & Psychology

How can knowing how DNA repairs itself help defeat cancer?

...class of drugs for treating cancer, known as PARP inhibitors. PARP – or poly-ADP ribose polymerase, to give it its full name – is a protein found in all our cells, and forms part of this backup repair system. It is particularly critical in cancer cells with faults in genes called BRCA1 or BRCA2, which play an important role in gluing together breaks in DNA. Errors in...
Ireland and the Battle of The Somme
OpenLearn Ireland

Ireland and the Battle of The Somme

...class, peace-trained soldiery had been expended, and the morale of its army shaken. The campaign had stretched its limited resources almost to breaking point. Thereafter its High Command changed tactics – no longer holding ground at all costs, and adopting the ‘Hindenburg Line’ (September 1916), so conceding much territory in order to shorten the front. The effect...
Uncertainty within the Realm of Statistics
Science, Maths & Technology

Uncertainty within the Realm of Statistics

...class action was brought and the injustice was rectified. We are just beginning to see the potential of big data and the matching of data sets. There will be many unforeseen consequences of this new technology – both positive and negative. Statistics are developing as a result of what technology can allow us to do. There will be new and exciting possibilities in the...
Sleep: A doctor's advice
Health, Sports & Psychology

Sleep: A doctor's advice

...classes or meditation help them. I teach my patients meditation exercises as they are easy to use in bed. Here are two very simple, but highly effective, techniques: Meditation This is simply focussed relaxation, and aims to stop you running thoughts in your mind that may be causing you stress and stopping you sleeping. By distracting you from your worries your mind has...
Does the rural idyll really exist?
Nature & Environment

Does the rural idyll really exist?

...class lifestyle that had developed in Coventry was then destroyed or at least severely damaged. I’m not surprised that growing up in the period inspired you to write the sort of music that you did. Terry: So what cities do you think have got it right? Dr Lincoln Allison: When you say get it right you can’t blame people too much. A lot of this is about history, it’s...
Global English
History & The Arts

Global English

...English may not prove to be a permanent phenomenon. It took centuries for Global English to develop and, like Latin, it may take centuries for its influence to decline. The global linguistic future is already looking more complex. Language learners in some parts of the world are already queuing for classes in Chinese, Spanish and Arabic. Read more articles like this...
Article 10 mins
Lifecycle of the Car Industry
Money & Business

Lifecycle of the Car Industry

...class of vehicle. Toyota, Volkswagen, Ford, Fiat, and other big manufacturers soon jumped onto what continues to be a very profitable bandwagon.The market for full size people carriers is now in its mature stage. As their share of the market dropped, Renault created a smaller version of the people carrier – the Megane Scenic. Once again other manufacturers have seen the...
Prison Abolition in Question(s): Part Two
Education & Development

Prison Abolition in Question(s): Part Two

...class inequality? Abolitionism is a way of saying NO to certain responses to problematic and harmful events. It calls us to beware of punishment and warn that it will not deliver justice. Justice is a central concern of abolitionists, but they focus on the broader concept of ‘social justice’. They argue that there is an obligation to build a social structure that can...