Science, Maths & Technology
Understanding interstrand crosslink repair in Drosophila
...health. When repair mechanisms are defective, humans become predisposed to a range of cancers. One kind of DNA damage for which effective repair is vital to humans, crosslinking of DNA. This occurs when various agents react with two different position in the DNA; in opposite strands of the DNA it is known as an interstrand crosslink (ICL). The presence of ICL results in...