Science, Maths & Technology
Understanding interstrand crosslink repair in Drosophila
...project exploits the genetic similarities between the fruit fly (Drosophila melanogaster) and humans in order to investigate and understand the role of the two related 3’-5’ exonucleases, CG7670 and CG6744 exonuclease, in the repair of interstrand crosslinks (ICL) in the fruit fly. Based on protein sequence and biochemical similarity the two exonucleases are closely...