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...concepts are similar. In each case, special molecules called endonucleases act as “molecular scissors” to create a break in a cell or organism’s DNA. Scientists design the endonucleases to only cut the DNA at a location they have chosen, usually an important part of a gene of interest. If the endonuclease has been designed correctly, DNA will be cut but poorly...

...concept. The key detail is that the endonuclease does not need to be re-engineered every time. Instead it is the guide RNA molecule that needs to be custom-made. This though, is a far easier proposition: guide RNAs can be synthesised in a matter of hours and purchased for as little as £10. CRISPR/Cas9 reduces weeks of work into a matter of days. It is this combination of...

...concept of logarithm with earlier ideas about progressions and trigonometrical formulae. What seems to you the most striking difference in overall approach? What problem do you see Napier’s work solving? Discussion The major difference is surely in his use of the concept of motion, of points moving along lines with speeds defined in various ways. Both exponents of...

...concepts that make up a conceptual whole that when understood can be used to increase the practical repertoire available through STiP. [Described image] Figure 1 The relationship between systemic and systematic practices, the two adjectives arriving from the word ‘system’ adopted in this course. Praxis is purposeful, practical action, or practice, informed by theory...