967 search results

Drug development process: combating pain
Science, Maths & Technology

Drug development process: combating pain

...central nervous system (CNS) associated conditions, is the need to achieve penetration of the blood–brain barrier, a process that has exacting physico-chemical requirements. A more detailed study would address these issues and illustrate the methods not only for discovering new active compounds, but also optimising these to ensure that they can perform effectively and...
Why the bands played on: Live music in the shadow of the Paris attacks
History & The Arts

Why the bands played on: Live music in the shadow of the Paris attacks

...central to the modern popular music economy, especially since the massive disruptions wrought by the internet on the recording industry. Under 6% of the new artists signed to UK major labels last year managed to achieve gold album status – with only three gold-selling debut records yet this year. Of course, there’s still big money in music. Increasingly, though,...
10 things that ended in 2006 (when OpenLearn was born)
History & The Arts

10 things that ended in 2006 (when OpenLearn was born)

...central Oklahoma] Yes, in 2006 the people of London found that they definitely weren't in Kansas anymore when the capital was hit by a tornado with an estimated T4 intensity on the TORRO scale. This weather, usually reserved for the likes of Torando Valley in the USA, struck the Kensal Green area of North-West London and tore through several streets in under a minute,...
No Pause for Thought? Brexit, Bias and Political Manipulation
Health, Sports & Psychology

No Pause for Thought? Brexit, Bias and Political Manipulation

...central newspaper is the Daily Mirror, with the headline "So what the hell happens now?"] Seeing Britain move into an uncertain and precarious future outside of the European Union is undoubtedly a defining moment in British and European history. In this context, the announcement of a General Election, to be held on the 8th of June, is a moment a moment to stop and...
What are nerve agents - and what do they do?
Science, Maths & Technology

What are nerve agents - and what do they do?

...central nervous system. The body uses a molecule called acetylcholine to send messages between cells – when an acetylcholine molecule “arrives”, it causes an electrical impulse to be sent. The body constantly has to remove those acetylcholine molecules from the receptors, otherwise there would be a dangerous build-up. It uses an enzyme called acetylcholinesterase...
Review: Building and Dwelling - Ethics for the City
Society, Politics & Law

Review: Building and Dwelling - Ethics for the City

...Central Park all shared the aim of refashioning the built environment to transform human behaviour. However, none of these contended with the unruly way people behave in the city. For example, for Georg Simmel, the growth of the modern city raises anxieties about the crowd, to which we respond by affecting indifference to our fellows. This divorce between the ville and...
What are your views about technologies to support and assess writing skills?
Education & Development

What are your views about technologies to support and assess writing skills?

...central process for developing and sharing understanding as well as building and disseminating knowledge. Students learn and are assessed through their writing, whereas professionals frequently use writing to organise their thinking, present their views and get feedback through peer-review - all supported by technologies. The digital age has enabled the read/write...
Will more money for the NHS deliver for midwife services?
Health, Sports & Psychology

Will more money for the NHS deliver for midwife services?

...central to the transformation of healthcare is being further undermined. The TUC-led All Together for the NHS campaign has spent the run up to this week’s Spending Review highlighting the various ways in which the government’s squeeze on NHS funding has impacted on different services. From A&E waiting times, to staff shortages, over-stretched GPs, cancer care and...