Science, Maths & Technology
Understanding interstrand crosslink repair in Drosophila
...adult progeria), patients have a defect (mutation) in the WRN gene (see fig2). Werner syndrome is characterized by the appearance of premature aging, therefore used as a model for understanding normal ageing process. In addition research into ICL repair mechanism enhances the understanding of cancer therapies that rely on ICL induction, such as genotoxic chemotherapy...