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...central’ scenario. Also, by understanding more of the complexity I find this aspect helps me to retain an open mind on most topics, aids reducing prejudice and helps me work to what I feel may be a more balanced viewpoint.’ John Robles: ‘It [systems thinking] allows me to tackle problems not only in a scientific way but in a holistic way which demonstrates a caring...

...central point called a hub. All messages are conveyed through the hub and, like the bus topology, will arrive at each node. In this arrangement, any single cable failure affects only one node, but a hub failure would make the entire network inoperable. Typically, the maximum number of nodes that can be connected together in a star topology is 24. To expand a star network,...

...central hydrophobic antiparallel β sheet, flanked by two short α helices (Figure 14b), which together form a compact flattened hemisphere with two surface pockets. The SH2 domain binds the phosphotyrosine-containing polypeptide substrate via these surface pockets (Figure 15). One pocket (phosphotyrosine pocket) represents the binding site for phosphotyrosine, whereas...