1,394 search results
Drug development process: combating pain
Science, Maths & Technology

Drug development process: combating pain

...analysis of ADME factors is usually described as ‘drug metabolism and pharmacokinetics’ or DMPK studies.) Taking the above factors fully into account improves the chances that any selected candidate will progress through to Phase 1 trials. Even then, at the present time, some 40% of candidates drop out of contention at the preclinical evaluation stage. Success in...
View course Drug development process: combating pain
Level 3: Advanced 2 hrs
Managing complexity: a systems approach
Society, Politics & Law

Managing complexity: a systems approach

...data are not the result of its own self-production. The way the computer works remains the same, whether it is processing pictures from the National Gallery or whether it is processing letters of the alphabet. The rules that relate input to output are constant over time. The question of what I can know about the outside world is an ancient one and has always been central...
View course Managing complexity: a systems approach
Level 3: Advanced 20 hrs
Why would you want to make a bee wear a backpack?
Nature & Environment

Why would you want to make a bee wear a backpack?

...data (if underpowered). Most bee monitoring occurs in carefully-controlled experimental conditions on relatively flat land. Current tracking systems are unable to monitor in landscapes that are anything other than flat as there needs to be a clear line of sight between the receiver and the transmitter attached to the bee. Knowing where and how bees move and die outside...
View article Why would you want to make a bee wear a backpack?
Article 5 mins
Will burnt food give you cancer?
Health, Sports & Psychology

Will burnt food give you cancer?

...data concluded that “dietary acrylamide is not related to the risk of most common cancers”. Although, it added that a modest association for kidney cancer, and for endometrial and ovarian cancers in people who had never smoked, couldn’t be ruled out. Meaty concerns Going back to the barbecue, there are other chemicals in meat that could be a concern. These generally...
View article Will burnt food give you cancer?
Article 5 mins
Hot forging (closed die)
Science, Maths & Technology

Hot forging (closed die)

...hot former (flashless in steel) 0.5–2˚ General design parameters are similar to those explained in the open die data card (excluding tolerances and draft angles). Flash removal can leave a witness mark that might have to be dressed by grinding or barrelling. See Also: Hot forging (open die), Cold forging, Warm forging, Powder forging and Isothermal precision forging....
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Article 5 mins
From ‘refrigerator mothers’ to paracetamol: why harmful autism myths are so common
Health, Sports & Psychology

From ‘refrigerator mothers’ to paracetamol: why harmful autism myths are so common

...data. Their findings have never been replicated in large-scale human research. This pattern is familiar from other autism “scares”. Early studies that suggested a link between ultrasound scans or prenatal stress and autism also relied on animal models and were not confirmed by large population studies. Myths that outlive the evidence Even when false claims are...
View article From ‘refrigerator mothers’ to paracetamol: why harmful autism myths are so common
Article 5 mins
Knife crime is a health risk for young people – it can’t be solved by policing alone
Education & Development

Knife crime is a health risk for young people – it can’t be solved by policing alone

...data that does exist is distorted, London-centric, and contrived from unverified police intelligence sources and the opinions of a small group of justice professionals and senior police officers. [A photo of Pekin Close, in Poplar, a London estate road, Canary Wharf in the background] Pekin Close, Poplar, London For my book, Race, Gangs and Youth Violence, I drew on young...
View article Knife crime is a health risk for young people – it can’t be solved by policing alone
Article 5 mins
How can we encourage people to mend their clothes?
Science, Maths & Technology

How can we encourage people to mend their clothes?

...data, a set of personas was created – imaginary but realistic characters that represent real patterns of behaviour. Let’s introduce them: The eco mender: mends to protect the planet The craft mender: loves turning repairs into creative projects The occasional mender: just fixes what they need, when they need it The delegating mender: prefers someone else to do the...
View article How can we encourage people to mend their clothes?
Article 5 mins