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...DNA transcription, protein synthesis or changes in metabolic activity. The overall effect of switching various processes on or off determines the consequent change in cellular behaviour. The fidelity, accuracy and appropriateness of these cellular communication processes are critically important for the cell and for the organism. It is well known that aberrant cellular...

...DNA-binding molecules, and thus regulate gene transcription (these are called receptors with intrinsic transcriptional activity; do not confuse with RIEAs). Some of these receptors are on the cell surface, but most are intracellular (Section 3.5), and require ready access of the ligand to the intracellular compartment. What sort of ligand might act on an intracellular...